Colin W. G. Fishwick: search on Z-Library

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1

Structures of Helical β-Tapes and Twisted Ribbons: The Role of Side-Chain Interactions on Twist and Bend Behavior

Fishwick, Colin W. G., Beevers, Andrew J., Carrick, Lisa M., Whitehouse, Conor D., Aggeli, Amalia, Boden, Neville

Journal:

Year:

2003

Language:

english

File:

PDF, 447 KB

english, 2003

2

Structure-based design of anti-infectives

Anil K Agarwal, Colin W. G. Fishwick

Journal:

Annals of the New York Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.26 MB

english, 2010

3

Interconvertible geometric isomers of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors exhibit multiple binding modes

McConkey, Glenn A., Bedingfield, Paul T.P., Burrell, David R., Chambers, Nicholas C., Cunningham, Fraser, Prior, Timothy J., Fishwick, Colin W.G., Boa, Andrew N.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 724 KB

english, 2017

4

Identification of an Indazole-Based Pharmacophore for the Inhibition of FGFR Kinases Using Fragment-Led De Novo Design

Turner, Lewis D, Summers, Abbey J, Johnson, Laura O, Knowles, Margaret A, Fishwick, Colin W. G.

Journal:

ACS Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 398 KB

english, 2017

5

Structure-switching M 3 L 2 Ir( iii ) coordination cages with photo-isomerising azo-aromatic linkers

Oldknow, Samuel, Martir, Diego Rota, Pritchard, Victoria E., Blitz, Mark A., Fishwick, Colin W. G., Zysman-Colman, Eli, Hardie, Michaele J.

Journal:

Chemical Science

Year:

2018

Language:

english

File:

PDF, 1.42 MB

english, 2018

6

Hetero-1,3-dipolar cycloadditions of dithiolane-isocyanate imminium methylides: A novel route to 1,3-oxazolidine- and thiazolidine-2-thiones

Colin W.G. Fishwick, Richard J. Foster, Robin E. Carr

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 168 KB

english, 1996

7

Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy

Uppal, Sandeep, Diggle, Christine P, Carr, Ian M, Fishwick, Colin W G, Ahmed, Mushtaq, Ibrahim, Gamal H, Helliwell, Philip S, Latos-Bieleńska, Anna, Phillips, Simon E V, Markham, Alexander F

Journal:

Nature Genetics

Year:

2008

Language:

english

File:

PDF, 607 KB

english, 2008

8

Dithiolane-isocyanate imminium methylides: A rapid stereoselective entry into γ-lactams

Colin W.G. Fishwick, Richard J. Foster, Robin E. Carr

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 216 KB

english, 1995

9

γ-Carboline AC190 analogues via palladium catalysed allene insertion stereo and regioselective 3- and 5-component cascades

Dondas, H. Ali, Hempshall, Aiden, Narramore, Sarah, Kilner, Colin, Fishwick, Colin W.G., Grigg, Ronald

Journal:

Year:

2016

Language:

english

File:

PDF, 1.80 MB

english, 2016

10

Facile preparation of 2-imino tetrahydrofurans, pyrans and oxepans

Alex I.D. Alanine, Colin W.G. Fishwick, Csaba Szantay Jr.

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 130 KB

english, 1989

11

ChemInform Abstract: The Azomethine Ylide Strategy for β-Lactam Synthesis. An Evaluation of Alternative Pathways for Azomethine Ylide Generation.

Giles A. Brown, Sarah R. Martel, Richard Wisedale, Jonathan P. H. Charmant, Neil J. Hales, Colin W. G. Fishwick, Timothy Gallagher

Journal:

Year:

2001

File:

PDF, 32 KB

2001

12

Three-component bimetallic (Pd/In) mediated cascade allylation of C=X functionality: Part 1. Scope and Class 1 examples with aldehydes and ketones

Laura A.T Cleghorn, Ian R Cooper, Colin W.G Fishwick, Ronald Grigg, William S MacLachlan, Marcello Rasparini, Visuvanathar Sridharan

Journal:

Journal of Organometallic Chemistry

Year:

2003

Language:

english

File:

PDF, 401 KB

english, 2003

13

Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2(3) by High-Throughput Virtual Screening and Automated Patch Clamp

Sören J. Wacker, Dr. Wiktor Jurkowski, Dr. Katie J. Simmons, Prof. Dr. Colin W. G. Fishwick, Prof. Dr. A. Peter Johnson, Dr. David Madge, Prof. Dr. Erik Lindahl, Dr. Jean-Francois Rolland, Prof. Dr. B

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

14

Encapsulation of sodium alkyl sulfates by the cyclotriveratrylene-based, [Pd6L8]12+ stella octangula cage

Cookson, Nikki J., Henkelis, James J., Ansell, Richard J., Fishwick, Colin W. G., Hardie, Michaele J., Fisher, Julie

Journal:

Dalton Transactions

Year:

2014

Language:

english

File:

PDF, 921 KB

english, 2014

15

Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovascular disease in diabetes

King, Rhodri, Tiede, Christian, Simmons, Katie, Fishwick, Colin, Tomlinson, Darren, Ajjan, Ramzi

Journal:

Year:

2015

Language:

english

File:

PDF, 52 KB

english, 2015

16

Tris - N -alkylpyridinium-functionalised cyclotriguaiacylene hosts as axles in branched [4]pseudorotaxane formation

Thorp-Greenwood, Flora L., Brennan, Alexander D., Oldknow, Samuel, Henkelis, James J., Simmons, Katie J., Fishwick, Colin W. G., Hardie, Michaele J.

Journal:

Supramolecular Chemistry

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

17

Synthesis of de novo designed small-molecule inhibitors of bacterial RNA polymerase

Anil K. Agarwal, A. Peter Johnson, Colin W.G. Fishwick

Journal:

Year:

2008

Language:

english

File:

PDF, 431 KB

english, 2008

18

X=Y–ZH system as potential 1,3-dipoles. Part 59: Cascade 1,3-azaprotio cyclotransfer–1,3-dipolar cycloaddition (1,3-APT–1,3-DC) reactions of benzobicyclo[3.3.1]non-5-en-9-one oxime

H.Ali Dondas, Colin W.G Fishwick, Ronald Grigg, Mark Thornton-Pett

Journal:

Year:

2003

Language:

english

File:

PDF, 499 KB

english, 2003

19

A CONVENIENT PREPARATION OF ETHYL 3,3 DIMETHYL-3H-INDOLE-2-CARBOXYLATE

Fishwick, Colin, Jones, Andrew, Mitchell, Michael

Journal:

Organic Preparations and Procedures International

Year:

1990

Language:

english

File:

PDF, 189 KB

english, 1990

20

Adenosine Tetraphosphoadenosine Drives a Continuous ATP-Release Assay for Aminoacyl-tRNA Synthetases and Other Adenylate-Forming Enzymes

Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I., Dowson, Christopher G.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 1.78 MB

english, 2013

21

The azomethine ylide strategy for β-lactam synthesis. An evaluation of alternative pathways for azomethine ylide generation

Brown, Giles A., Martel, Sarah R., Wisedale, Richard, Charmant, Jonathan P. H., Hales, Neil J., Fishwick, Colin W. G., Gallagher, Timothy

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2001

Language:

english

File:

PDF, 217 KB

english, 2001

22

Computational Methods to Identify New Antibacterial Targets

McPhillie, Martin J., Cain, Ricky M., Narramore, Sarah, Fishwick, Colin W. G., Simmons, Katie J.

Journal:

Chemical Biology & Drug Design

Year:

2015

Language:

english

File:

PDF, 781 KB

english, 2015

23

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, Fülöp, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 922 KB

english, 2017

24

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc 1 complexes for structure-based drug discovery

Amporndanai, Kangsa, Johnson, Rachel M., O'Neill, Paul M., Fishwick, Colin W. G., Jamson, Alexander H., Rawson, Shaun, Muench, Stephen P., Hasnain, S. Samar, Antonyuk, Svetlana V.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

25

A short dipolar cycloaddition approach to γ-lactam alkaloids from cynometra hankei

Colin W.G. Fishwick, Richard J. Foster, Robin E. Carr

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 195 KB

english, 1996

26

Formation and mechanistic implication of a novel thiaazabicyclooctane derivative drug the cycloaddition of n-acetyl cinnamic acid thioamide

Csaba Szántay Jr., István Moldvai, Colin W.G. Fishwick, David R. Hill

Journal:

Tetrahedron Letters

Year:

1991

Language:

english

File:

PDF, 340 KB

english, 1991

27

Intramolecular [3+2] cycloadditions of non-stabilised azomethine imidate-methylides

Alex I.D. Alanine, Colin W.G. Fishwick

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 172 KB

english, 1989

28

Preparation of methyl-2-(ω-iodoalkyl)propenoates and a facile route to 2-carbomethoxy-1,3-butadiene

Alex I.D. Alanine, Colin W.G. Fishwick, Andrew D. Jones, Michael B. Mitchell

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 129 KB

english, 1989

29

Intramolecular [3+2] cycloaddition versus 1,4-hydrogen shift in indolium-N-methylides

Colin W.G. Fishwick, Andrew D. Jones, Michael B. Mitchell

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 117 KB

english, 1989

30

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.

Journal:

Scientific Reports

Year:

2015

File:

PDF, 94 KB

2015

31

Catalytic bimetalic [Pd(0)/Ag(I) Heck-1,3-dipolar cycloaddition cascade reactions accessing spiro-oxindoles. Concomitant in situ generation of azomethine ylides and dipolarophile

Millington, Emma L., Dondas, H. Ali, Fishwick, Colin W.G., Kilner, Colin, Grigg, Ron

Journal:

Year:

2018

Language:

english

File:

PDF, 881 KB

english, 2018

32

Facile palladium catalysed functionalisation of 1,2-isothiazoline-3-ones

Andrew S. Bell, Colin W.G. Fishwick, Jessica E. Reed

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 275 KB

english, 1994

33

Generation and cycloadditions of 2-(N-acylamino)-1-thia-1,3-dienes

Ian T. Barnish, Colin W.G. Fishwick, David R. Hill, Csaba Szantay Jr.

Journal:

Tetrahedron Letters

Year:

1989

Language:

english

File:

PDF, 224 KB

english, 1989

34

Two novel amino acid derivatives containing side-chain thioamides for the synthesis of photoactivatable peptides

Preeti Singh, Craig R. Hurrell, John B.C. Findlay, Colin W.G. Fishwick

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

35

Discovery of Biphenylacetamide-Derived Inhibitors of BACE1 Using de Novo Structure-Based Molecular Design

Mok, N. Yi, Chadwick, James, Kellett, Katherine A. B., Casas-Arce, Eva, Hooper, Nigel M., Johnson, A. Peter, Fishwick, Colin W. G.

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 545 KB

english, 2013

36

Stereoselective Palladium-Catalyzed Four-Component Cascade Synthesis of Pyrrolidinyl-, Pyrazolidinyl-, and Isoxazolidinyl Isoquinolines

H. Ali Dondas, Colin W. G. Fishwick, Xinjie Gai, Ronald Grigg, Colin Kilner, Nuethip Dumrongchai, Boonsong Kongkathip, Ngampong Kongkathip, Chatchwan Polysuk, Visuvanathar Sridharan

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 200 KB

english, 2005

37

Stereoselective Palladium-Catalyzed Four-Component Cascade Synthesis of Pyrrolidinyl-, Pyrazolidinyl-, and Isoxazolidinyl Isoquinolines

H. Ali Dondas, Colin W. G. Fishwick, Xinjie Gai, Ronald Grigg, Colin Kilner, Nuethip Dumrongchai, Boonsong Kongkathip, Ngampong Kongkathip, Chatchwan Polysuk, Visuvanathar Sridharan

Journal:

Angewandte Chemie International Edition

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

38

Generation and cycloadditions of 2-(N-Acylamino)-1-thia-1,3-dienes. Part II. Rationalization of reactivity using an FMO approach.

Ian T. Barnish, Colin W.G. Fishwick, David R. Hill, Csaba Szanta Jr.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.16 MB

english, 1989

39

Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases

Bedingfield, Paul T. P., Cowen, Deborah, Acklam, Paul, Cunningham, Fraser, Parsons, Mark R., McConkey, Glenn A., Fishwick, Colin W. G., Johnson, A. Peter

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 502 KB

english, 2012

40

The reaction of benzyne with imines

Fishwick, Colin W. G., Gupta, Ramesh C., Storr, Richard C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 302 KB

english, 1984

41

Design and Synthesis of Potent Inhibitors of the Malaria Parasite Dihydroorotate Dehydrogenase

Heikkilä, Timo, Ramsey, Christopher, Davies, Matthew, Galtier, Christophe, Stead, Andrew M. W., Johnson, A. Peter, Fishwick, Colin W. G., Boa, Andrew N., McConkey, Glenn A.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 191 KB

english, 2007

42

Novel Generation and Regio- and Stereospecific 1,3-Dipolar Cycloaddition of 2-Ethoxycarbonyl-3,3-dimethyl-3 H -indolium-1-methanide

Fishwick, Colin W. G., Jones, Andrew D., Mitchell, Michael B., Eggleston, Drake S., Baures, Paul W.

Journal:

Year:

1990

File:

PDF, 163 KB

1990

43

ChemInform Abstract: Facile Palladium-Catalyzed Functionalization of 1,2-Isothiazoline-3-ones and the Highly Diastereoselective Diels—Alder Reactions of 4-Vinyl-1,2-isothiazoline-3-one-1-oxides.

Andrew S. Bell, Colin W. G. Fishwick, Jessica E. Reed

Journal:

Year:

2000

File:

PDF, 34 KB

2000

44

[3+2] Cycloadditions of indolenine-derived azomethine ylides a rapid entry into pyrrolo [1,2-a] indolines.

Colin W.G. Fishwick, Andrew D. Jones, Michael B. Mitchell, Csaba Szantay Jr

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 206 KB

english, 1988

45

The synthesis and reactivity of optically pure amino acids bearing side-chain thioamides

Sanderson, John M., Singh, P., Fishwick, Colin W. G., Findlay, John B. C.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

2000

Language:

english

File:

PDF, 115 KB

english, 2000

46

Identification of a small molecule inhibitor of Ebola virus genome replication and transcription using in silico screening

Easton, Victoria, McPhillie, Martin, Garcia-Dorival, Isabel, Barr, John N., Edwards, Thomas A., Foster, Richard, Fishwick, Colin, Harris, Mark

Journal:

Antiviral Research

Year:

2018

Language:

english

File:

PDF, 1.30 MB

english, 2018

47

Preparation of novel 3H-trifluoromethyldiazirine-based photoactivatable potassium channel antagonists

John M. Sanderson, John B.C. Findlay, Colin W.G. Fishwick

Journal:

Year:

2005

Language:

english

File:

PDF, 404 KB

english, 2005

48

pH as a Trigger of Peptide β-Sheet Self-Assembly and Reversible Switching between Nematic and Isotropic Phases

Aggeli, Amalia, Bell, Mark, Carrick, Lisa M., Fishwick, Colin W. G., Harding, Richard, Mawer, Peter J., Radford, Sheena E., Strong, Andrew E., Boden, Neville

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 286 KB

english, 2003

49

(±) cis-bisamido epoxides: A novel series of potent FXIII-A inhibitors

Avery, Craig A., Pease, Richard J., Smith, Kerrie, Boothby, May, Buckley, Helen M., Grant, Peter J., Fishwick, Colin W.G.

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 680 KB

english, 2015

50

The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors

Katy L. Blake, Alex J. O'Neill, Dominique Mengin-Lecreulx, Peter J. F. Henderson, Julieanne M. Bostock, Colin J. Dunsmore, Katie J. Simmons, Colin W. G. Fishwick, Jennifer A. Leeds, Ian Chopra

Journal:

Molecular Microbiology

Year:

2009

Language:

english

File:

PDF, 435 KB

english, 2009

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